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Why Can an Opioid Overdose Cause Death?

By May 30, 2024August 7th, 2024Sober living

which drug overdose can cause sudden death

In most emergency rooms, patients who present with an unknown cause of lethargy or loss of consciousness have their blood glucose levels drawn. The issue with poorly treated pain has led medical professionals to use all types of short and long-acting opiates, and while this has made a difference in relieving pain, some patients often do not remain compliant with proper dosing. When the patient increases the dose or duration of opioids, then toxicity is a potential complication. Although annual rates of transition are low, this is commonly caused by individuals transitioning from the nonmedical use of prescription opioids to heroin. Most studies originated from North America (40.5%) or Europe (39.2%). Case-control (47.3%) or cohort (40.5%) studies were the most common designs.

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They may also find items or substances related to the overdose near the person. Prescription opioids are involved in about 25% of all opioid overdose deaths. Nonprescription opioids account for about 75% of opioid overdose deaths. The medication naloxone is used to reverse opioid overdoses and works by attaching to mu-receptors to prevent opioids’ effects. This is particularly relevant for people with opioid use disorders and leaving prison, as they have very high rates of opioid overdose during the first four weeks after release. An NCHS report released last year showed the age-adjusted rate of US drug overdose deaths increased dramatically from 1999 (6.1 per 100,000 population) to 2016 (19.8 per 100,000).

Deterrence and Patient Education

An opioid overdose happens when opioids excessively stimulate the part of your brain that regulates breathing. This leads to respiratory depression (ineffective breathing) and can cause death if it isn’t treated in time. Finally, drugs most frequently recorded in unintentional overdose deaths in 2016 were fentanyl, heroin, and cocaine. The most frequently cited drugs in suicide by overdose were oxycodone, diphenhydramine, hydrocodone, and alprazolam. To our knowledge, this is the first scoping review that analyses the risk of the drugs related to sudden death and the methodology used. We identified 74 studies, being the first cohort study assessing the risk of cardiac death in patients with AF treated with antiarrhythmic drugs [14].

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which drug overdose can cause sudden death

For severe withdrawal cases, one may use clonidine, especially when methadone may be inappropriate or unavailable. After the acute treatment, the patient should be recommended to join a long-term drug rehabilitation program to prevent relapse. The half-life of naloxone is about 30 to 45 minutes with a duration of action between 90 to 180 minutes. The variations exist because of the route of administration and dose.

  1. To prevent an overdose, follow a doctor’s directions for all prescription medications.
  2. If there is any doubt about the patient’s clinical status, admission is prudent.
  3. An opioid overdose can happen if a person has overloaded their body with medications or illicit drugs, or a combination of opioids and other medications, drugs, or alcohol.

The autonomic symptoms may include excessive lacrimation, sweating, piloerection, rhinorrhea, repeated yawning, myalgia, nasal congestion, diarrhea, and abdominal cramps. The symptoms usually peak between 36 to 48 hours and gradually subside in 72 hours. The use of additional opiates to counter the symptoms of withdrawal is not recommended.

What can you do to prevent an opioid overdose?

It is a priority for CBC to create products that are accessible to all in Canada including people with visual, hearing, motor and cognitive challenges. “We really need both components to be part of this response,” he said. “We need to invest in reduction … to keep people alive so they can eventually access treatment.”

Collaboration is essential for success in preventing opioid overdose deaths. Together, we can better coordinate efforts to prevent opioid overdoses and deaths. In early 2015, the US Dept of Health and Human Services acknowledged the expanded use of naloxone among healthcare professionals to counter opiate overdoses in the nation.

Temporary changes have made it easier for people enrolled in methadone treatment to take doses home with them, instead of requiring them to visit a clinic each day. Ms. LaBelle said more people in drug treatment had stayed enrolled as a result. Regulators also made it easier for people to seek medical care through telemedicine, another policy that may be extended beyond the Covid emergency. For the first time, federal funds (from the recent stimulus bill) can be used to buy needles and syringes for exchange programs, and to purchase rapid fentanyl test strips, which can be used to check whether drugs contain fentanyl.

Now, pharmacists, emergency medical personnel, and physicians can all play an active role in the prevention of opiate overdose. In addition, the current recommendations also suggest co-prescription of naloxone to patients who are prescribed opiates. Several studies are showing that patients who had been prescribed naloxone at the same time as an opiate have fewer opiate-related emergency room visits than those who did not receive naloxone. Today, some healthcare workers have started to prescribe naloxone to patients who are prescribed high doses of opiates. The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum) as well as semisynthetic and synthetic compounds with similar properties that can interact with opioid receptors in the brain.

In fact, several deaths have been reported in drug abusers with the needle still in the arm. One other synthetic derivative, 3-Methylfentanyl, is several thousand times more potent than morphine and when people overdose on it, extremely high doses of intravenous naloxone https://rehabliving.net/ecstasy-symptoms-and-warning-signs/ infusions are required. Deaths from these fentanyl derivatives often occur in clusters as the sellers go from street to street, leading to multiple deaths along the way. If you or someone you know uses opioids, it’s important to carry naloxone in case of an overdose.

She became hypoglycemic, which caused her dizziness then her loss of consciousness and her fall. Hypoglycemia can be deadly because our human cells rely on sugar to live. From 2015 to 2016, the number of deaths from lab-made opioids, including fentanyl and chemical kin such as carfentanil (used to tranquilize large animals), more than doubled in the United States.

Although many drug overdoses involve the use of illegal drugs, it is also possible to overdose on prescription medication. These medications carry a high risk of addiction and overdose, especially if taken outside a doctor’s directions. This can include https://sober-house.org/what-are-the-immediate-short-term-effects-of/ taking any amount of someone else’s medication or more than the doctor prescribed. However, acute lung injury can also occur following methadone and propoxyphene overdose and is universally present in patients who expire from a high dose of opiate.

If you or a loved one has opioid use disorder, talk to a healthcare provider as soon as possible. Opioid use disorder is a medical condition — it requires https://sober-home.org/substance-use-and-co-occurring-mental-disorders/ care just like any other condition. Drug overdose is the leading cause of accidental death in the United States, with opioids being the most common cause.

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